Table of Contents
Washington University Experience | NEOPLASMS (EMBRYONAL) | Medulloblastoma, Histologically Defined | Extensive Nodularity (MBEN) | 3A4 Medulloblastoma, desmoplastic (Case 3) H&E 4X
The neoplasm is composed of two histologic patterns. One is composed small, atypical cells with elongated nuclei, inconspicuous nucleoli, and a coarse chromatin pattern. They have inconspicuous cytoplasm and show high mitotic activity as well as a large amount of apoptotic debris. The second pattern consists of round nuclei with relative stippling of chromatin, in a loose, neuropil-like background, forming round and elliptical islands, indicating neuronal differentiation.
