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Washington University Experience | NEOPLASMS (EMBRYONAL) | Medulloblastoma, Histologically Defined | Extensive Nodularity (MBEN) | 8F2 Medulloblastoma, desmoplastic (Case 8) b-catenin 4

Beta catenin shows cytoplasmic staining without nuclear localization. The intensity of the stain is increased in nodular areas. ---- Comment: FISH did not show evidence of isochromosome 17q (found in a subset of medulloblastomas), nor did it show an amplification of C-MYC or N-MYC

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