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Washington University Experience | NEOPLASMS (EMBRYONAL) | Medulloblastoma, Histologically Defined | Large cell-Anaplastic (LCA) | 13A1 Medulloblastoma, LCA (Case 13) H&E 10X
Case 13 History ---- [9yo male who underwent resection of a cerebellar mass followed by chemotherapy and radiation] ---- 13A1-5 Sections of the resected cerebellar mass show a high grade primitive central nervous system neoplasm. Tumor cells are arranged in markedly hypercellular sheets separated by hyalinized microvessels. A small amount of cerebellar parenchyma shows tumor cells in the subarachnoid space. Neoplastic cytology is noteworthy for very high nucleus to cytoplasm ratio, extensive nuclear molding and cell wrapping, nuclear hyperchromasia and very high mitotic rate. (H&E)
