Table of Contents

Washington University Experience | NEOPLASMS (EMBRYONAL) | Medulloblastoma, Histologically Defined | Large cell-Anaplastic (LCA) | 14A2 Medulloblastoma, large cell (Case 14) H&E 1

This is a malignant small blue cell tumor composed of sheets of pleomorphic cells that have hyperchromatic nuclei, scant cytoplasm, and high mitotic activity. Many of the nuclei are modestly enlarged and contain prominent nucleoli. However, cell-cell wrapping is not identified. Clusters of apoptotic cells are present in areas. (H&E)

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