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Washington University Experience | NEOPLASMS (EMBRYONAL) | Medulloblastoma, Histologically Defined | Large cell-Anaplastic (LCA) | 8A1 Medulloblastoma, LCA (Case 8) H&E 7 - Copy.jpg
Case 8 History ---- [4yo male who presents with nausea and vomiting to an outside hospital. MRI shows a large heterogeneously post-contrast enhancing mass in the fourth ventricle. Operative procedure: Craniotomy excision of posterior fossa mass. ---- 8A1-4 A hypercellular malignant round cell tumor. There are areas of necrosis. The tumor has a sheet-like growth pattern with some areas of vague nodularity but is not compelling for the diagnosis of desmoplastic medulloblastoma. The tumor cells have scant to no distinct cytoplasm. There are areas with large nuclei, prominent moulding, cell wrapping and nucleoli. Mitotic figures are frequent.
