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Washington University Experience | NEOPLASMS (EMBRYONAL) | Medulloblastoma, Histologically Defined | Medullomyoblastoma | 5A1 Medullomyoblastoma (W21-2112) H&E 20X

5A1 Medullomyoblastoma (W21-2112) H&E 20X
5A1-3 The provided sections show sheets of a markedly hypercellular neoplasm with a high-nucleus-to-cytoplasm ratio. The tumor cells have round to elongate nuclei, and the majority of cells have only minimal amounts of cytoplasm (i.e., a “small blue cell” phenotype). Scattered throughout the tumor are numerous cells with rounded or elongated bellies of eosinophilic cytoplasm, consistent with rhabdoid and strap-cell differentiation. Mitotic activity is brisk. Rosettes are not conspicuous.



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