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Washington University Experience | NEOPLASMS (GLIAL) | Astrocytoma, IDH-mutant, WHO Grade 4 | 11A1 IDHmut Astro Gr4 (Case 11) H&E 3.jpg
Case 11 History ---- The patient was a 32 year old female who underwent gross total section in January of 2010 and adjuvant radiotherapy. Recent tumor recurrence led to a reresection in 2016. ---- 11A1-3 The tumor shows hypercellular sheets separated by thin-walled, branching vessels, some forming garlands of microvascular proliferation. Necrosis is absent. The infiltrating tumor cells have small, moderately to severely pleomorphic, hyperchromatic nuclei that display occasional multinucleation, mitotic activity, focally marked contour irregularity and widespread perinuclear clearing.
