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Washington University Experience | NEOPLASMS (GLIAL) | Astrocytoma, IDH-mutant, WHO Grade 4 | 11A2 IDHmut Astro Gr4 (Case 11) H&E 2.jpg
The tumor shows hypercellular sheets of infiltrating tumor cells have small, moderately to severely pleomorphic, hyperchromatic nuclei that display occasional multinucleation, mitotic activity, focally marked contour irregularity and widespread perinuclear clearing.