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Washington University Experience | NEOPLASMS (GLIAL) | Astrocytoma, IDH-mutant, WHO Grade 4 | 2A3 IDHmut Astro Gr4 (Case 2) H&E 40X
The neurosurgical specimen shows neuroglial tissue infiltrated to varying degrees by a frankly malignant glioma with widespread microvascular proliferation, multinucleation, pseudopalisading necrosis and vascular thrombosis. There is severe nuclear atypia and mitotic figures are abundant.