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Washington University Experience | NEOPLASMS (GLIAL) | Astrocytoma, IDH-mutant, WHO Grade 4 | 5A5 IDHmut Astro Gr4 (Case 5) H&E 20X 2
This is a high grade glioma with hypercellularity, marked pleomorphism, high mitotic rate, and multifocal endothelial hyperplasia. Tumor cells are markedly pleomorphic. Ectatic blood vessels with hyalinized walls are also present, consistent with radiation change.
