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Washington University Experience | NEOPLASMS (GLIAL) | Astrocytoma, pilocytic - Microscopic | 50E Astrocytoma, pilocytic (Case 50) Sox10 2X
Not shown: Tumor cells are positive for Olig2 (subset). They are negative for IDH1 R132H, BRAF V600E, and H3K27M mutant proteins. A p53 immunostain demonstrates wild-type expression. ---- Fluorescence in situ hybridization studies are positive for BRAF rearrangement, suggestive of KIAA1549- BRAF fusion.