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Washington University Experience | NEOPLASMS (GLIAL) | Diffuse midline glioma, H3 K27-altered | 1G3 Glioma, Diffuse Infiltrating Pontine (DIPG, Case 1) NF 40X
Higher magnification of neurofilament immunohistochemistry in the medulla shows transverse and enface descending tract elements. (NF IHC) ---- Neuro Final Diagnosis: DMG, H3 K27M-mutant, WHO grade 4, centered in the pons with extension into the midbrain and medulla and scattered infiltration into cerebellum, temporal lobe, basal ganglia, thalamus, occipital lobe, and neurohypophysis.