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Washington University Experience | NEOPLASMS (GLIAL) | Diffuse midline glioma, H3 K27-altered | 4B3 Diffuse midline glioma, (Case 4) H&E 3
Tumor cells have indistinct cytoplasm with elongated atypical nuclei featuring hyperchromasia, coarse chromatin, and irregular nuclear contours. Mitotic figures are readily identified. There are focal areas of incipient necrosis but no evidence of microvascular proliferation.