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Washington University Experience | NEOPLASMS (GLIAL) | Ependymoma, myxopapillary | 15A1 Ependymoma, myxopapillary (Case 15) H&E WM
Case 15 History ---- The patient is a 43 year old woman who originally presented 3 years prior with low back pain and numbness in the hands and feet. MR imaging of the spine performed in 2012 showed a conus intramedullary or intradural mass without enhancement or abnormal signal cephalad to the mass. The patient underwent surgical resection. Follow-up MR imaging performed in August 2012 showed two persistent ovoid enhancing masses at the L2 level. ---- 15A1-5 Sections show a proliferation of spindled to cuboidal cells with round-to-ovoid nuclei, elongated eosinophilic processes, and occasional, moderate nuclear atypia. Papillary architecture is somewhat inconspicuous. Many of the vessels appear hyalinized. There are focal areas of myxoid background stroma, although many areas are solid. Microvascular proliferation and necrosis are not identified. Small round, spiculated "collagen balloons" are noted.
