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Washington University Experience | NEOPLASMS (GLIAL) | Glioblastoma, epithelioid | 3A1 Gliosarcoma (Case 3) Epithelioid area H&E 5

Case 3 History ---- The patient was an 80 year-old man who presented with memory problems and an enhancing left temporal lobe mass on MRI. ---- Slides show a high-grade neoplasm with a biphasic appearance. Microvascular proliferation and necrosis is present. The glial component is highly cellular and composed of pleomorphic astrocytic cells with marked nuclear atypia and increased mitotic activity. ---- 3A1-3 The morphology in the glial component includes vacuolated and epithelioid areas.

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