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Washington University Experience | NEOPLASMS (GLIAL) | Glioblastoma, primitive neuronal component | 14C1 GBM, PNET & epithelioid (Case 14) B4 SYN area A 40X 2.jpg
14C1,2 Interestingly, the majority of epithelioid tumor cells as well as small primitive cells display strong synaptophysin reactivity, including perinuclear dot-like accentuation. Given the presence of epithelioid morphology, we performed IHC for mutant BRAF (p.V600E), but this stain was negative.