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Washington University Experience | NEOPLASMS (GLIAL) | Glioblastoma, primitive neuronal component | 18F3 GBM with PNET features (Case 18) Ki67 20X
Ki-67 shows increased staining: approximately 25-50% of tumor cell nuclei stain in high grade glioma component and >75% in PNC component). (Ki67 IHC) ---- Ancillary stains (not shown) Tumor cells are negative for the mutant form of IDH1 (R132H). MGMT (O(6)-methylguanine-DNA methyltransferase) gene methylation was detected using methylation specific PCR technologies.
