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Washington University Experience | NEOPLASMS (GLIAL) | Glioblastoma, primitive neuronal component | 19A3 GBM with PNET and Giant Cell (Case 19) GBM area H&E 4.jpg
A typical glioblastoma area is pleomorphic and a subset of tumor cells have a giant cell morphology with enlarged 'bizarre', and sometimes multinucleated, cells.