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Washington University Experience | NEOPLASMS (GLIAL) | Glioblastoma, primitive neuronal component | 2F GBM, PNET (Case 2) FISH nmyc cep 2 100x - Copy
2F FISH study showed NMYC amplification but not CMYC. ---- Ancillary studies (not shown): No reactivity is observed for mutant IDH1 (R132H). Neurofilament immunoreactivity highlights many entrapped axons within the glioma component; these are largely excluded from the PNET component, consistent with a solid growth pattern.