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Washington University Experience | NEOPLASMS (GLIAL) | Glioblastoma, small cell type | 20A3 GBM, small cell type (Case 20) H&E 4

Numerous bipolar cells, frequent mitoses and prominent areas of pseudo-palisading necrosis are noted. Ancillary studies (not shown): FISH There were polysomies (gains) of chromosome 19. No deletions were found, i.e., especially 1p/19q. ---- Methylation of the MGMT (O(6)-methylguanine-DNA methyltransferase) gene was not detected using methylation specific PCR technologies.

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