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Washington University Experience | NEOPLASMS (GLIAL) | Glioblastoma, small cell type | 8B GBM, focal small cell (Case 8) EGFR Amp

8B GBM, focal small cell (Case 8) EGFR Amp
FISH studies provide evidence of polysomy of chromosome 7, EGFR gene amplification and chromosome 10q deletion. There was no evidence of 1p/19q deletions. ---- An immunohistochemical stain for p53 shows scattered strong positivity. The neoplastic cells are negative for mutant IDH1 (R132H).


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