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Washington University Experience | NEOPLASMS (GLIAL) | Glioblastoma, small cell type | 8B GBM, focal small cell (Case 8) EGFR Amp
FISH studies provide evidence of polysomy of chromosome 7, EGFR gene amplification and chromosome 10q deletion. There was no evidence of 1p/19q deletions. ---- An immunohistochemical stain for p53 shows scattered strong positivity. The neoplastic cells are negative for mutant IDH1 (R132H).