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Washington University Experience | NEOPLASMS (GLIAL) | Glioblastoma - Gross Pathology | 28A0 Case 28 History
Case 28 History ---- This 55 year old right handed male was initially admitted to the Neurology Service in November 1977 with a month history of mild headache and a 1 week history of dizziness. He had marked vertical nystagmus on upgaze and endpoint nystagmus on right and left lateral gaze. A CT scan revealed a large bilobed mass in the left frontal area. The patient underwent a left frontal craniotomy on 11/28/77 with removal of a glioblastoma. The patient did well postoperatively and was discharged with a normal neurological examination except for bilateral lateral endgaze nystagmus. The patient underwent a course of radiation therapy. He was readmitted to Barnes Hospital in October 1978 complaining of recurrent frontal headaches exacerbated with standing. A CT scan revealed an enlarging left frontal enhancing mass. Over the ensuing two months the patient experienced marked deterioration in mental status. He was readmitted to BJH on 2/19/79 where an examination revealed a confused middle-aged male. The gait was consistent with motor apraxia and he tended to fall to either side. The patient was felt to have marked recurrence of his glioblastoma. The patient continued to deteriorate over the next 4 days and on 3/16/ 79 the patient was found to have no respirations, pulse, or blood pressure.
