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Washington University Experience | NEOPLASMS (GLIAL) | Glioblastoma - Gross Pathology | 6A0 Case 6 History
Case 6 History ---- The patient was a 44 year old male who presented in October of 1980 with transient expressive aphasia and a right hemiparesis. A CT scan showed multiple contrast enhancing lesions in the left frontal and parietal regions. The diagnosis of probable glioblastoma was made based on radiographic appearance and the patient's clinical history. The patient was treated with whole brain irradiation with a total dose of 5913 RADS, anticonvulsants, and Decadron. Nine months prior to death, he was admitted to BH to receive high dose BCNU and an autologous bone marrow rescue was performed. There was little tumor response as evidenced on the CT scan. The ensuing months were complicated by numerous problems including extensive venous thrombosis of the lower extremities requiring placement of an inferior vena cava umbrella and a mild interstitial pneumonitis felt to represent a complication of the BCNU therapy. Four months prior to his death, the patient received a one week course of procarbazine which was complicated by early myelosuppression. There is no record of the patient's examination just prior to death.
