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Washington University Experience | NEOPLASMS (GLIAL) | Gliosarcoma | 4B1 Gliosarcoma, chondroid and osteoid (Case 4) H&E 2X Area 1
The neurosurgical specimen is a high-grade diffuse glioma (glioblastoma with WT IDH1, retained ATRX, p53 weak to moderate reactivity in a subset of tumor cells.) with both fibrillary and gemistocytic components. Microvascular proliferation is identified but no definitive necrosis is seen.