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Washington University Experience | NEOPLASMS (GLIAL) | Gliosarcoma | 9A1 Gliosarcoma (Case 9) 2 H&E

Case 9 History ---- The patient was a 50 year-old woman presenting with headache and decreased level of consciousness for one week. MRI showed a large contrast-enhancing right temporal tumor. ---- This is a high grade astrocytic neoplasm composed of pleomorphic cells with irregular hyperchromatic nuclei and increased mitotic activity. Microvascular proliferation and pseudopalisading necrosis are present. ---- 9A1There is a single nodule within the tumor whole mount which displays sarcomatous differentiation. (H&E)

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