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Washington University Experience | NEOPLASMS (GLIAL) | Oligodendroglioma - IDH1 mutant, del 1p19q - Grade 2 | 1A3 Oligodendroglioma (Case 1) H&E 5
The neoplastic cells have round regular nuclei with crisp nuclear envelopes, peri-nuclear cytoplasmic clearing, peri-neuronal satellitosis and hexagonal ('chicken-wire') branching. The lesion shows increased mitotic activity, ranging up to 4 mitotic figures/10HPF. There is no evidence of necrosis.