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Washington University Experience | NEOPLASMS (GLIAL) | Oligodendroglioma - IDH1 mutant, del 1p19q - Grade 2 | 20A2 Oligodendroglioma, WHO II (Case 20) H&E 5.jpg
Sections of the resected left frontal tumor show a diffuse glioma with oligodendroglial differentiation. At its infiltrative edge, there is perivascular and perineuronal satellitosis. Neoplastic cells are arranged in variably hypercellular sheets with a rich investment by small vessels. There is no necrosis or microvascular proliferation. Neoplastic cells have relatively uniform oval to round nuclei with extensive cytoplasmic clearing. Calcifications are scattered within the neoplasm. Mitotic activity is present but insufficient for the diagnosis of anaplastic oligodendroglioma.
