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Washington University Experience | NEOPLASMS (GLIAL) | Oligodendroglioma - IDH1 mutant, del 1p19q - Grade 3 | 11C Oligodendroglioma, anaplastic (Case 11) Ki67 1
KI-67 confirms brisk proliferative activity. ---- Not shown: p53 faintly stains scattered tumor nuclei and ATRX shows retained nuclear expression. ---- Comment: The genetic and histologic features are diagnostic of an oligodendroglial tumor. The presence of microvascular proliferation and brisk cell division warrant the WHO grade III designation.