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Washington University Experience | NEOPLASMS (GLIAL) | Pleomorphic Xanthoastrocytoma (PXA) | 10A2 PXA & GG (Case 10) H&E 4
The tumor nuclei range from spindled to irregular and hyperchromatic, with scattered multinucleated giant cells. There are numerous eosinophilic granular bodies and occasional Rosenthal fibers. Perivascular and intratumoral lymphocytic accumulation is identified.