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Washington University Experience | NEOPLASMS (GLIAL) | Pleomorphic Xanthoastrocytoma (PXA) | 12F2 PXA (Case 12) EM 004 - Copy

A xanthomatous tumor cell shows cytoplasmic lipid droplets. (electron micrographs) ---- Ancillary data (not shown): Neurofilament immunostaining demonstrates an infiltrative pattern. CD3 demonstrates T-lymphocytes within the tumor and focal perivascular cuffing. Neoplastic cells are negative for synaptophysin and IDH1. Ki-67 shows a proliferative index of 1.0%. ---- Comment: The findings are those of a pleomorphic xanthoastrocytoma, WHO grade 2.

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