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Washington University Experience | NEOPLASMS (GLIAL) | Subependymal Giant Cell Astrocytoma (SEGA) | 2B1 Astrocytoma, SEGA (Case 2) Area A H&E 10X
2B1-5 Images show a low grade neoplasm composed of phenotypically variable tumor cells. The neoplastic cells are spindled to epithelioid or gemistocyte-like (often mimicking neuronal/ganglion-like cells) and contain moderate to abundant eosinophilic cytoplasm with vesicular nuclei showing focal prominence of nucleoli. There is mild to moderate pleomorphism within the tumor cells; however, mitoses are difficult to find and necrosis is not evident. The tumor has a capillary rich vasculature and shows patchy chronic inflammatory cell infiltrate.
