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Washington University Experience | NEOPLASMS (GLIAL) | Subependymoma | 8B Subependymoma (Case 8) GFAP 1
The tumor cells are diffusely positive for GFAP. ---- EMA highlights rare paranuclear dot-like reactivity. Synaptophysin and NeuN are negative. D2-40 has a high background and shows both nuclear, cytoplasmic, and paranuclear dot-like reactivity in a subset of tumor cells. Ki-67 highlights a proliferative index of < 1%.