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Washington University Experience | NEOPLASMS (METASTASES) | Melanoma | 10A1 Melanoma (Case 10) H&E 20X
Case 10 History ---- The patient is a 65-year-old woman presenting with a brain tumor and no known primary neoplasm. Operative procedure: Left parietal craniotomy for tumor resection with spinal cord monitoring, motor mapping, MEP, SSEP. ---- 10A1,2 H&E stained sections show a high-grade malignant neoplasm composed of ovoid to spindled cells with moderate pleomorphism and indistinct cell borders. The tumor cells have a small to moderate amount of eosinophilic cytoplasm, and many show 'cherry red' nucleoli. The background tissue shows frequent deposits of melanin pigment including in macrophages. (H&E)