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Washington University Experience | NEOPLASMS (METASTASES) | Melanoma | 11A1 Melanoma (Case 11) H&E 20X
Case 11 History ---- The patient is a 62-year-old woman with a history of melanoma who presents with an enhancing brain lesion. Operative procedure: craniotomy for tumor excision. ---- 11A1-4 H&E-stained sections show brain parenchyma infiltrated by a metastatic pigmented neoplasm composed of moderately pleomorphic cells with amphophilic cytoplasm. The tumor cells have atypical nuclei with lightly granular chromatin and 'cherry-red' nucleoli. Mitoses are abundant, and the background tissue shows extensive hemorrhage.
