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Washington University Experience | NEOPLASMS (METASTASES) | Microscopic | 14A Metastasis, frontal bone, medullary thyroid origin (Case 14) H&E 3
Case 14 History ---- The patient is a 71-year-old man with a history of medullary thyroid cancer, who on interval imaging had evidence of an 0.8 cm, right frontal, mildly enhancing bone lesion with possible involvement of the underlying leptomeninges. Operative procedure: Right frontal craniectomy and biopsy. ---- 14A The tumor cells have enlarged, hyperchromatic nuclei, speckled chromatin, occasional prominent nucleoli, scant to moderate amounts of eosinophilic cytoplasm, amyloid deposition, and are arranged in a cribriform architecture or in small nests. There are scattered mitotic figures.
