Table of Contents

Washington University Experience | NEOPLASMS (NEURONAL) | Central Neurocytoma | 9A1 Neurocytoma, central (AANP 1999, Case 3) H&E X1

Case 9 History (AANP DSS 1999, Case 3) ---- The patient is a 28 year old right handed woman who was well until December 1997 when she was hit by a bicycle and lost consciousness for several minutes. In the following weeks she developed new onset headaches associated with nausea and vomiting. One week prior to admission she began complaining of difficulty concentrating at work. At this time, her boyfriend also noticed clumsiness in the use of her hands while eating. On 4/24/98, the patient went to the emergency room because of a particularly severe headache and vomiting. She had bilateral mild papilledema, but otherwise normal cranial nerve testing. On admission, a head MRI showed a 5 x 6 x 8 cm multicystic heterogeneous mass centered in the region of the septum pellucidum, extending into the lateral ventricles with compression of the foramina of Monro bilaterally, resulting in obstructive hydrocephalus. The mass partially enhanced with gadolinium. There was also bilateral uncal herniation, and downward brainstem herniation. The patient was started on Decadron and received intermittent mannitol for severe headaches and vomiting. On the fifth hospital day, a craniotomy was performed. ---- 9A1-5 This is an excellent example of a central neurocytoma with seas of bland round neurocytes and a few mitoses. (H&E)

---