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Washington University Experience | NEOPLASMS (NEURONAL) | Paraganglioma - Cauda Equina Neuroendocrine Tumor | 13A1 Paraganglioma (Case 13) H&E 20X
Case 19 History ---- The patient is a 34yo male with chronic pain in his left lower extremity and severe exacerbation. MRI shows a solitary intradural extramedullary enhancing mass. Operative procedure: Lumbar laminectomy for excisional biopsy intradural lesion. ---- 19A1-3 H&E-stained sections show a neoplasm arranged in ‘zellballen” or a nested pattern separated by thin fibrovascular septa. The predominant chief cells are polygonal and demonstrate regular round to oval nuclei with finely stippled chromatin and inconspicuous nucleoli. The cytoplasm is eosinophilic and finely granular. The sustentacular cell population is not prominent. Mitoses are fairly abundant, up to 5/10 high power fields.
