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Washington University Experience | NEOPLASMS (PINEAL) | Pineocytoma | 12A1 Pineocytoma (AFIP 1965 Study Set Slide 79) H&E 4X
Case 12 History (AFIP Teaching Set, Case #79) ---- The patient was a 69-year-old woman who developed headaches, backaches, and some difficulty in walking over a 2- year period. Increasing weakness and apathy eventually confined her to bed. Pneumonia developed, and the patient expired. Prior to death, papilledema and increased spinal fluid pressure had been noted. A pneurnoencephalogram made some time before death suggested a midline brain tumor. ---- Gross pathology: Examination of the brain showed a large, partially cystic tumor in the area of the pineal body, pushing into the third ventricle and compressing the midbrain. ---- 12A1-3 This section shows a tumor with moderate cellularity and delicate connective tissue stroma. Perivascular rosettes are frequently seen and pineocytomatous rosettes are prominent. Some cystic areas filled with pale eosinophilic granular material are seen in the background. The nuclei of the tumor cells are uniform with dusky nucleoplasm and coarse chromatin granules. Mitotic figures are not seen, and nucleoli are not prominent. (H&E)
