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Washington University Experience | NEOPLASM (SELLAR) | Pituitary Adenoma - Pituitary Neuroendocrine Neoplasm | Corticotroph | 2C2 PA (Case 2) Crooke's CAM52 3.jpg
There is a cytoplasmic concentric ring like staining pattern for cytokeratin CAM 5.2 in a minor subpopulation of tumor cells, not reaching anything like 50% of the tumor population. ---- Not shown: The Ki-67 proliferative index is 0.9%. ---- The morphologic and immunophenotypic findings are those of a corticotroph pituitary adenoma with focal Crooke’s hyaline change.
