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Washington University Experience | NEOPLASM (SELLAR) | Pituitary Adenoma - Pituitary Neuroendocrine Neoplasm | Plurihormonal | 1B1 PA, Pluri (Case 1) PRL 4X
There are significant differences in the cellular population of both regions. One consists of basophilic, minimally granular small cells (1A4) and the second is composed of a larger eosinophilic markedly granular cell population (1A5). There are significant hormonal content differences in these populations as well (see following). (H&E) ---- 1B1,2 Prolactin (PRL) immunohistochemistry: 1B1 This PRL immunostain highlights the richly labeled tumor cells in the 1A1 arrowhead region.