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Washington University Experience | NEOPLASM (SELLAR) | Pituitary Adenoma - Pituitary Neuroendocrine Neoplasm | Plurihormonal | 8A0 Case 8 History
Case 8 History ---- The patient is a 48 year old female with MEN1 syndrome. Patients with multiple endocrine neoplasia type 1 (MEN1) exhibit neuroendocrine tumors consisting of pituitary adenomas, parathyroid adenomas and neuroendocrine tissue of gastro-entero-pancreatic organ systems. The patient has a history of longstanding hypertension and some features of acromegaly that include enlarging nasal structures and increasing hand and shoe size. MRI of the head showed a 1.7 cm hypo-enhancing mass in the sella, slightly left of midline. She also was found to have clinically asymptomatic hyperparathyroidism. A parathyroid radionucleotide scan (SPECT) showed a 3.3 cm lesion consistent with a large parathyroid adenoma on the left, just below the inferior pole of the left lobe of the thyroid. Operative procedures: Transsphenoidal resection of pituitary tumor and parathyroidectomy.
