Table of Contents
Washington University Experience | NEOPLASMS - CRANIAL AND PARASPINAL NERVEs | Malignant Peripheral Nerve Sheath Tumor (MPNST) | 16A2 MPNST with Meissner's (Case 16) H&E 3
Sections from the right gluteal mass show a spindle cell neoplasm comprised of spindle cell nuclei with few atypical large bizarre nuclei and eosinophilic cytoplasm. Rare mitoses are seen, however no atypical forms are noted. There is no evidence of necrosis. ---- Focally, there are numerous Meissner's corpuscles (arrow, 16A3) within the tumor. Normally these structures lie between the dermal papillae just beneath the epidermis of the fingers, palms, and soles. Commonly they involve neurofibromas of the skin. They are formed of elongated Schwann cells, a connective tissue capsule and a central axon and represent cutaneous receptors for fine touch.
