16A3 MPNST with Meissner's (Case 16) H&E 2 copy | Malignant Peripheral Nerve Sheath Tumor (MPNST) | NEOPLASMS - CRANIAL AND PARASPINAL NERVEs

Washington University Experience | NEOPLASMS - CRANIAL AND PARASPINAL NERVEs | Malignant Peripheral Nerve Sheath Tumor (MPNST) | 16A3 MPNST with Meissner's (Case 16) H&E 2 copy

Focally, there are numerous Meissner's corpuscles (arrow) within the tumor. Normally these structures lie between the dermal papillae just beneath the epidermis of the fingers, palms, and soles. Commonly they involve neurofibromas of the skin. They are formed of elongated Schwann cells, a connective tissue capsule and a central axon and represent cutaneous receptors for fine touch.

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Washington University Experience | NEOPLASMS - CRANIAL AND PARASPINAL NERVEs | Malignant Peripheral Nerve Sheath Tumor (MPNST) | 16A3 MPNST with Meissner's (Case 16) H&E 2 copy