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Washington University Experience | NEOPLASMS - CRANIAL AND PARASPINAL NERVEs | Malignant Peripheral Nerve Sheath Tumor (MPNST) | 1C1 MPNST (Case 1) whole mount 1

1C1,2 Histological sections of the cervical paraspinal mass show a neoplasm that is arranged in generally well- circumscribed nodules (fascicles) with an intraneural growth pattern; in three dimensions, these 'nodules' are interconnected. The larger nodules have a fibrous pseudocapsule, but lack a true, well-defined capsule. No normal-appearing nerve fascicles are identified in the periphery of these tumor nodules. (H&E)

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