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Washington University Experience | NEOPLASMS - CRANIAL AND PARASPINAL NERVEs | Malignant Peripheral Nerve Sheath Tumor (MPNST) | 4A3 MPNST (Case 4) rhabdomyoblast differentiation H&E

4A3 MPNST (Case 4) rhabdomyoblast differentiation H&E
Hematoxylin and eosin stained sections of the resection show a tumor composed of alternating hypercellular fascicles and less cellular fibrous to myxoid regions. The hypercellular areas consist of crowded, variably atypical spindled cells with hyperchromatic, tapered nuclei, numerous mitoses (up to 10/10 HPF) and apoptotic bodies.



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