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Washington University Experience | NEOPLASMS - CRANIAL AND PARASPINAL NERVEs | Malignant Peripheral Nerve Sheath Tumor (MPNST) | 9G MPNST (Case 9) MIB 1
The proliferative index is high (Ki67 IHC). ---- There is loss of p16, a cell cycle regulatory protein. The morphologic features and immunohistochemical staining profile is consistent with a high grade malignant peripheral nerve sheath tumor, WHO grade IV.
