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Washington University Experience | NEOPLASMS - CRANIAL AND PARASPINAL NERVEs | Neurofibroma | 13A1 Neurofibroma, plexiform (Case 13) H&E whole mount

Case 13 History ---- The patient is a 40-year-old woman who initially presented with paresthesias of the left leg and was found to have a lobulated, multiseptated T2 hyperintense lesion extending along the course of the left femoral nerve from the neural foramina to the inguinal ligament by MRI. Operative procedure: Excision of femoral nerve neurofibroma with adductor nerve to femoral nerve transfer for reconstruction. ---- 13A1,2 The three neurospecimens all show a plexiform neurofibroma. There are multiple nerve bundles showing large variation in shape and size. The bundles are haphazardly arranged and contain abundant amounts of mucin. The nerve bundles are separated by large amounts of connective tissue consisting of mature adipose tissue, fibrous tissue, and multiple small to medium sized vessels.

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