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Washington University Experience | NEOPLASMS - CRANIAL AND PARASPINAL NERVEs | Neurofibroma | 7B1 Neurofibroma in NF1 patient (Case 7) H&E 2.jpg
7B1-3 Sections of the C4-C7 tumors show moderately cellular proliferations of spindled cells growing in a vaguely fascicular architecture. The cells demonstrate wavy, somewhat elongated, nuclei with tapered ends, some of which show mild atypia. Scattered mast cells are identified. Mitotic activity is not identified. Several large entrapped ganglion cells are noted. Per the operative summary, the tumors at C4, C5 and C7 showed integration of the nerve roots in a diffuse pattern without a clear plane of resection.
