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Washington University Experience | NEOPLASMS - CRANIAL AND PARASPINAL NERVEs | Schwannoma - Cellular | 4C Schwannoma, cellular (Case 4) Coll IV 20X
The tumor has nearly diffuse immunoreactivity collagen IV although the staining intensities vary among different regions. ---- Not shown: Stains for EMA, neurofilament, CD34 and smooth muscle actin (SMA) are negative. The proliferative activity of this tumor illustrated by the labeling index of Ki-67 is generally low with focal increases to a moderate level. The histomorphologic features and immunoprofile are consistent with a cellular schwannoma.