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Washington University Experience | NEOPLASMS (HEMATOLYMPHOID) | ALK Fusion Histiocytosis | 1H2 ALK-positive Histiocytosis (Case 1) GFAP 20X 1
Involvement of brain parenchyma provokes a proliferation of GFAP astrocytes (GFAP IHC) Additional Studies: FISH studies show ALK gene rearrangement. Send out to Cincinatti Childrens report:shows ALK+ (ALK-rearranged) Histiocytosis. Foundation One Heme, a comprehensive genomic profiling test, showed ALK KIF5B-ALK fusion.
